Nanoparticulate system for cancer therapy: An updated review |
Author : Dharmendra Kumar* and Pramod Kumar Sharma |
Abstract | Full Text |
Abstract :Nowadays, pharmaceutical nanotechnology has been developed as the most emerging branch in the field of pharmacy. “Nanotechnology refers to the nanosize formulation. These nanoformulations may be used in treatment of various life-threading diseases like cancer. Due to the advantages of their nano size and shape, nanoformulations have been shown to be favorable drug delivery systems and may be useful for encapsulating and conjugating of drugs, enabling most precise tumor targeting and controlled release. Nanoparticle drug delivery system have several advantages such as enhanced intracellular infi ltration, hydrophobic solubility, and drug circulation time and also reduce nonspecifi c uptake and toxic effect for cancer therapy. A large number of Nanoparticle technologies have been developed for cancer treatment to improve the therapeutic effi cacy and safety for anticancer drugs. In this paper, we review the most signifi cant advancement in pharmaceutical nanotechnologies with methods of preparation and their usein drug delivery for cancer therapy. |
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Preparation of nanocellulose and its potential application |
Author : Latifah Jasmania* and Wim Thielemans |
Abstract | Full Text |
Abstract :Nanostructured cellulose has received tremendous attention due to its inherent unique properties such as high strength, high surface area, flexible surface chemistry, abundant and renewable. The early polymers industry was nearly completely bio-based and cellulose was one of the most important materials. It has only been the Second World War that changed things and propelled petroleum, as the main source material. Due to global awareness on the use of more green products, cellulose offers an alternative to petroleum-based products. This paper presents the general overview of nanocellulose starting from its cellulose structure and properties to preparation of nanocellulose, properties and its potential application. |
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A Microwave- irradiated Novel Superabsorbent Polymer Hydrogel (Guar gum-g- PAA): Synthesis, characterization and property studies |
Author : Pramilarani Behera, Tikina Rani Sethy and Prafulla K Sahoo* |
Abstract | Full Text |
Abstract :The main aim of the present study was to synthesize Guar gum grafted poly acrylic acid (Gg-g-PAA) superabsorbent polymer (SAP) hydrogel via free radical emulsifier-free emulsion graft polymerization technique using microwave irradiation. The so prepared superabsorbent polymer hydrogel was characterized by Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM). The properties like swelling ability and biodegradability were also studied which has a profound influence in agriculture, biomedicine, pharmaceutics, etc. The SAP may potentially be used for the fast release of medicine in high pH environment. It also may have found its application and sustainability in the removal of heavy metal ions from the waste water through adsorption leading to water remediation. |
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